IKA EasySyn 2000 Advanced Synthesis Reactor, Reactor Volume 2,000 ml, RS232/USB, 0010016811

On the 2 litre scale, scale-up work often only becomes truly meaningful, because process engineering effects such as heat removal, mixing time and stirring power show up more clearly than in the smaller vessel sizes of the series, while at the same time the demands on documentation and reproducibility increase. The IKA EasySyn 2000 Advanced (0010016811) combines a complete reactor system for 2,000 millilitres of reaction volume with a digital interface: via RS232 and USB, the stirrer can be connected to a PC and automated with the laboratory software labworldsoft 6, an important criterion when process data have to be recorded without gaps for later evaluation or documentation in a GLP environment. Compared with the Starter version of the same size, the Advanced model is aimed at laboratories that depend on digital traceability of their synthesis parameters.

2,000 millilitre reactor vessel with DN 150 flange

The double-walled reactor vessel SY 2000 D is made of borosilicate glass 3.3 and has a bottom outlet with a spring-loaded valve spindle against glass breakage. At DN 150, the flange connection is sized one size larger than on the smaller 500 and 1,000 millilitre models of the series (SY clamp 150, SY clamping ring 150, FEP-coated SY O-ring 150). The reactor lid SY 150.1 offers four openings: an NS 29/32 centre joint for the stirrer as well as two further NS 29/32 and one NS 14/23 connection, for example for reflux condensers or an additional temperature sensor. As with the smaller models of the series, both the borosilicate glass and the FEP-coated O-ring are resistant to a wide range of solvents here as well, an important factor with more aggressive reaction media in scale-up.

EUROSTAR 100 control: more torque and digital connection

Instead of the EUROSTAR 60 digital of the Starter variant with its 60 Ncm, the Advanced model uses the more powerful EUROSTAR 100 control stirrer to drive the PTFE-coated pitched-blade stirrer R 4012 SY. It covers a speed range of 0/30 to 1,300 revolutions per minute and delivers up to 100 Ncm of torque at the stirring shaft, more reserve for more viscous media in the larger vessel than the EUROSTAR 60 digital of the Starter variant. In addition to the RS232 and USB interface, a timer, overload protection and temperature measurement are integrated directly in the stirrer. An integrated torque trend display also makes changes in viscosity during the reaction visible, a useful additional indicator particularly with larger batch quantities on the 2 litre scale, when the stirring characteristics change in the course of the synthesis.

Draining set LT 5.40 for quick batch changes

The scope of delivery of the Advanced version also includes the draining set LT 5.40. Via its own valves provided specifically for this purpose, the temperature control liquid can be drained from the double jacket without residue, which noticeably speeds up changing between different reactor vessels or test series on the 2 litre scale, particularly relevant when a reactor has to be reconfigured several times during the working day. Without this set, the temperature control liquid would have to be drained awkwardly via the hose connections of the double jacket before every vessel change.

Vacuum, temperature range and usable volume

The stirrer shaft guide allows vacuum operation down to 3 mbar. The materials used are approved for temperatures from minus 50 to plus 200 °C, and the permissible ambient temperature for operation itself is between 5 and 40 °C. The vessel can be used from 120 millilitres of filling volume, and with the temperature sensor immersed the minimum usable volume rises to 400 millilitres. The stirrer shaft guide (SY guide) seals the passage of the stirring shaft through the reactor lid and is thus a prerequisite for vacuum operation.

Ergonomic stand system with quick vessel change

The working height of the stand adapts to the operator and allows swift exchange of the 2 litre reactor vessel via the DN 150 clamp. Together with the draining set LT 5.40, the double jacket can be emptied without residue before the vessel change, which saves time particularly in scale-up trials with several successive batches per day.

Typical applications

With digital process documentation, the EasySyn 2000 Advanced is particularly suitable for scale-up work with increased documentation requirements:

• Scale-up trials with gap-free process documentation via labworldsoft 6
• Automated syntheses with several reaction steps and reproducible conditions
• Production of larger sample batches for analysis, formulation or customer samples
• Process development with frequent vessel changes thanks to the draining set LT 5.40
• Transition from laboratory towards pilot scale with increased documentation requirements

Technical details

Scope of delivery

• 1 x SY stand
• 1 x reactor vessel SY 2000 D (2,000 ml, borosilicate glass 3.3, with bottom outlet)
• 1 x SY clamp 150
• 1 x SY clamping ring 150
• 1 x SY O-ring 150 (FEP-coated)
• 1 x reactor lid SY 150.1
• 1 x pitched-blade stirrer R 4012 SY (PTFE-coated)
• 1 x EUROSTAR 100 control stirrer
• 1 x quick-release chuck R 60
• 1 x draining set LT 5.40
• 1 x stirrer shaft guide

Not included are temperature control hoses for connecting an external circulating thermostat, and the thermostat itself. The automation software labworldsoft 6 is likewise not part of the scope of delivery but is available separately.

Regulatory information

The EUROSTAR 100 control stirrer is an electrical appliance within the meaning of the German Electrical and Electronic Equipment Act (ElektroG). The WEEE registration number of the manufacturer IKA is DE 66784213. Information on returning old appliances can be found on our page Environment and disposal.

Individual requirements & procurement service

For extending the EasySyn 2000 Advanced, we offer further original accessories through our procurement service, for example additional reactor vessels and reactor lids, stirring tools in other designs, seal sets, suitable circulating thermostats for temperature control of the double jacket, and the automation software labworldsoft 6. We are also happy to help you put together a complete temperature control system or with spare parts. Further information and contact options can be found on our service page.

The manufacturer's warranty from IKA applies to the EUROSTAR 100 control stirrer as the drive of the system: 2 years, extended to 3 years if registered at ika.com/register within 90 days of purchase.