Memmert HPP110eco Constant-Temperature Chamber, 108 litres, Peltier technology without a compressor

Anyone embarking on stability testing in accordance with ICH Q1A or looking to expand their existing testing capacity with a compact chamber will find it hard to overlook one name: the Memmert HPP110eco constant-climate chamber, with an internal volume of 108 litres, delivers precisely the combination of controlled temperature and humidity that quality assurance and research require to produce reliable results. Heating and cooling are provided by a Peltier element in the rear wall, without the need for a compressor or conventional refrigerant, which reduces both maintenance requirements and noise levels in day-to-day laboratory work.

Peltier cooling without a compressor or refrigerant

Unlike conventional climate chambers with compressor cooling, the HPP110eco operates using a Peltier heating and cooling system based on the heat pump principle. The element is located in the rear wall and handles both heating and cooling; there is no need for a separate refrigerant or a CFC circuit. Depending on the operating mode, the chamber covers 0 to 70 °C without humidity control or 5 to 70 °C with active humidity control; when light is applied, the operating range narrows to 15 to 40 °C, as stipulated by most stability protocols involving light exposure anyway. Two DIN Class A Pt100 sensors in a 4-wire configuration monitor each other and automatically take over the function of the other sensor in the event of a fault; this reduces the risk of an undetected sensor failure during a test series lasting several weeks.

Humidity control and ControlCOCKPIT TwinDISPLAY

Relative humidity can be controlled between 10 and 90 % rh with a setting accuracy of 0.5 % rh; humidification is provided by a hot steam generator, whilst dehumidification is achieved via a cold trap using Peltier technology. The system is supplied via an external water canister with a connecting hose; a fixed water connection is not required, which also makes it easier to set up the unit away from a water mains supply. The HPP110eco is operated via the ControlCOCKPIT TwinDISPLAY, comprising two high-resolution TFT colour graphic displays for the simultaneous display of temperature and humidity, with a choice of languages including German, English, French and Chinese. The SetpointWait function only starts the actual test period once the temperature and humidity have actually reached the setpoint – a detail that ensures reproducible start times for time-critical stability protocols.

Selection guide: Choosing the right model from the HPPeco range

The HPP110eco is the smallest of the four constant-climate chambers from the HPPeco series compared here and is suitable for laboratories starting out with just a few batches per test run or looking to supplement an existing larger chamber with a compact unit for special tests. With up to 5 shelves and a maximum load capacity of 150 kg, it is sufficient for smaller sample quantities; for a greater number of parallel runs, it is worth considering its larger counterparts:

Anyone who regularly requires more than 5 shelves at the same time or stores several batches in parallel under different ICH conditions is usually better served by the Memmert Constant-Climate Chamber HPP260eco or the Memmert Constant-Climate Chamber HPP410eco; technically, the control system, safety features and humidity system are identical across all four sizes. You can find an overview of the entire Memmert range of climate chambers and incubators at LT Laborhandel in the ‘Climate Chambers & Incubators’ category.

Choosing between the HPPeco and the ICH110?

If you also require temperatures below 0 °C or prefer compressor-based cooling with automatic defrosting, the Memmert ICH110 climate cabinet offers a suitable alternative in the same 108-litre volume class. The ICH110 cools and heats via an air-jacket temperature control system using the CFC-free refrigerant R290 and covers an operating range from -10 to +60 °C; however, at around 1,350 W, it requires significantly more power than the HPP110eco, which draws around 420 W. However, for those working between 0 and 70 °C without a compressor or refrigerant and with lower energy requirements, the Peltier technology of the HPP110eco is the better choice.

Installation, water connection and drainage

For operation, a minimum clearance of 15 cm from the wall, a maximum clearance of 20 cm from the ceiling and a minimum clearance of 5 cm at the sides must be maintained; installation is permitted at altitudes of up to 2,000 m above sea level at ambient temperatures of 16 to 40 °C and a maximum relative humidity of 70 per cent, non-condensing. Humidity is supplied via the water canister supplied with the unit, which includes a connection hose and a self-priming pump; a fixed water connection in the installation room is not required. At the end of its service life, the HPP110eco must be disposed of as waste electrical and electronic equipment; Memmert is listed with the Stiftung Elektro-Altgeräte Register (Stiftung EAR) under WEEE registration number DE 66812464.

Investment rationale: Which equipment for which test purpose

Before placing an order, it is worth considering what additional equipment the chamber requires beyond the basic configuration. For documented, validatable test runs, a USB-to-Ethernet adapter for data transfer and AtmoCONTROL or myChamber software licences are recommended; on request, these are also available in an FDA-compliant version for environments subject to 21 CFR Part 11. For unattended runs overnight or at weekends, a dry contact for connection to a central building management system or a MobileALERT SMS alert system are recommended. If the chamber is to be shared amongst several user groups with different access rights, a lockable door with a security lock or a USB user ID stick for the TwinDISPLAY can be added. For the installation itself, there is also a choice of a castor frame, levelling feet, a stacking kit for space-saving combinations of several chambers, and a levelling or mobile base frame.

Typical applications

With an internal volume of 108 litres, Peltier cooling and active humidity control, the Memmert HPP110eco constant-climate chamber is particularly in demand where compact test capacity is required for recurring but not high-volume test series.

• Stability studies of individual batches of active ingredients in accordance with ICH Q1A in pharmaceutical quality assurance
• Stability tests for cosmetic formulations on a smaller development scale
• Supplementary test chamber alongside a larger HPPeco chamber for special conditions or peak capacity requirements
• Material testing in industrial quality assurance
• Environmental testing from freezing point upwards in research and development

Frequently asked questions about the Memmert HPP110eco constant-climate chamber

What temperature and humidity range does the HPP110eco cover?
Depending on the operating mode, 0 to 70 °C without humidity or 5 to 70 °C with active humidity control between 10 and 90 % rh; with light exposure, the operating range is restricted to 15 to 40 °C.

Does the chamber require a fixed water connection?
No. Humidity is supplied via the water canister supplied with the unit, complete with a connecting hose; a self-priming pump delivers the distilled water as required.

How many samples can fit into the HPP110eco?
Two shelves are included as standard; a total of up to five shelves, each with a maximum load of 20 kg, can be fitted, though the total load must not exceed 150 kg.

Is the HPP110eco suitable for ICH stability testing?
Yes, according to the manufacturer’s specifications, the chamber is designed for stability studies in accordance with ICH guidelines (Q1A) as well as for stability tests in the cosmetics and food industries.

What distinguishes the HPP110eco from the Memmert ICH110 climate chamber?
The HPP110eco uses a Peltier element to cool between 0 and 70 °C without a compressor or refrigerant, whilst the ICH110 operates with a compressor-based refrigeration cycle (R290) and also covers a range down to -10 °C.

What software is available for documentation and validation?
The chamber can be managed via the Ethernet interface using the AtmoCONTROL software; an FDA-compliant licence version is also available for environments subject to 21 CFR Part 11.

How is calibration carried out?
A calibration certificate is supplied as standard (reference values: 25 °C at 60 % rh and 40 °C at 75 % rh); in addition, three freely selectable values each for temperature and humidity can be calibrated by the user. LT Laborhandel arranges suitable services for DAkkS-accredited calibrations as well as IQ/OQ/PQ.

Technical details

Scope of delivery

• 1x Memmert HPP110eco constant-climate chamber
• Standard factory calibration certificate (25 °C / 60 % rh, 40 °C / 75 % rh)
• Fully insulated stainless steel door with 2-point locking (compression door seal)
• Inner glass door
• Moisture-proof silicone feed-through (internal diameter 18 mm) with silicone plug
• 2x stainless steel grating, electropolished
• Water canister including connection hose

Regulatory information

The Memmert HPP110eco constant-climate chamber is registered with the Stiftung Elektro-Altgeräte Register (Stiftung EAR) under WEEE registration number DE 66812464.

Customised requirements & procurement service

Optional extras available for the HPP110eco include a castor frame with a supply air filter, levelling feet, a stacking kit for operating multiple chambers one on top of the other, and a levelling or mobile base frame. For data acquisition, a USB-to-Ethernet adapter and AtmoCONTROL and myChamber software licences are available; FDA-compliant licences are also available. In addition, we arrange calibration, IQ/OQ/PQ and maintenance services, including those accredited by DAkkS. Do you require any of these accessories, a special configuration, or assistance in selecting the right size for your application? Through our procurement service, LT Laborhandel will be happy to assist you with procurement and configuration.